神戸学院大学 薬学部 製剤学研究室
Laboratory of Pharmaceutical Technology
2017
97. 山本昌弘，田崎真一，飯島志行，市川秀喜，福森義信，神谷秀博： pH応答性薬剤カプセルと粘膜の表面間力に対してカプセル内部の架橋が及ぼす影響のコロイドプローブAFM法による評価. 粉体工学会誌，54, 305-310 (2017).
96. Takayuki Kamata, Koichi Wada, Hideki Ichikawa: Dry pre-coating of active pharmaceutical ingredient with submicron-sized hydroxypropylcellulose in dry granulation using roller compactor improves granule properties. J. Drug Deliv. Sci. Tech., in press.
2015
95. Yuya Hattori, Kazunori Kadota, Taichi Yano, Atsuko Shimosaka, Hideki Ichikawa, Yoshinobu Fukumori, Yoshiyuki Shirakawa, Jusuke Hidaka. Fabrication of composite particles through single pass using a coaxial tube reactor. Chemical Engineering and Processing: Process Intensification, Volume 97, November 2015, Pages 233–241.
94. Fujimoto T, Andoh T, Sudo T, Fujita I, Fukase N, Takeuchi T, Sonobe H, Inoue M, Hirose T, Sakuma T, Moritake H, Sugimoto T, Kawamoto T, Fukumori Y, Yamamoto S, Atagi S, Sakurai Y, Kurosaka M, Ono K, Ichikawa H, Suzuki M., Potential of boron neutron capture therapy (BNCT) for malignant peripheral nerve sheath tumors (MPNST). Appl Radiat Isot. 106, 220-225 (2015).
93. Andoh T, Fujimoto T, Suzuki M, Sudo T, Sakurai Y, Tanaka H, Fujita I, Fukase N, Moritake H, Sugimoto T, Sakuma T, Sasai H, Kawamoto T, Kirihata M, Fukumori Y, Akisue T, Ono K, Ichikawa H., Boron neutron capture therapy (BNCT) as a new approach for clear cell sarcoma (CCS) treatment: Trial using a lung metastasis model of CCS. Appl Radiat Isot. 106, 195-201 (2015).
92. Karmaker, S., Uddin, M.N., Ichikawa, H., Fukumori, Y., Saha, T.K., Adsorption of reactive orange 13 onto jackfruit seed flakes in aqueous solution. Journal of Environmental Chemical Engineering, 3(1), 583-592 (2015).
91. 大野 優太, 安藤 徹, 津江 晋一郎, 杉澤 賢司, 福森 義信, 市川 秀喜, ドラフトチューブ付き噴流層スプレーコーターによる超低粘度ヒドロキシプロピルセルロースを用いた微小核粒子への薬物レイヤリング．粉体工学会誌、52(3), 145-149 (2015).
90. Onodera T, Kuriyama I, Andoh T, Ichikawa H, Sakamoto Y, Lee-Hiraiwa E, Mizushina Y. Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion. Int J Mol Med., 35(6), 1720-1728 (2015).)
2014
89. Hojo K, Shinozaki N, Hidaka K, Tsuda Y, Fukumori Y, Ichikawa H, Wade JD, Microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: racemization studies and water-based synthesis of histidine-containing peptides. Amino Acids, 46(10), 2347-54 (2014)
88. Ichikawa H, Uneme T, Andoh T, Arita Y, Fujimoto T, Suzuki M, Sakurai Y, Shinto H, Fukasawa T, Fujii F, Fukumori Y., Gadolinium-loaded chitosan nanoparticles for neutron-capture therapy: Influence of micrometric properties of the nanoparticles on tumor-killing effect. Appl Radiat Isot, 88, 109-13 (2014).
87. Andoh, Tooru; Fujimoto Takuya, Sudo Tamotsu, Suzuki Minoru, Sakurai Yoshinori, Sakuma Toshiko, Moritake Hiroshi, Sugimoto Tohru, Takeuchi Tamotsu, Sonobe Hiroshi, Epstein AL, Fukumori Y, Ono K, Ichikawa H., Boron neutron capture therapy as new treatment for clear cell sarcoma: Trial on different animal model. Applied Radiation and Isotopes, 88, 59-63 (2014).
2013
86. Keiko Hojo*, Natsuki Shinozaki, Yoshimi Nozawa, Yoshinobu Fukumori, Hideki Ichikawa, Aqueous Microwave-Assisted Solid-Phase Synthesis Using Boc-Amino Acid Nanoparticles．Appl. Sci., 3, 614-623 (2013).
85. Keiko Hojo,* Natsuki Shinozaki, Asaki Hara, Mare Onishi, Yoshinobu Fukumori and Hideki Ichikawa. Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy. 11. Racemization Studies and Water ßased Synthesis of Cysteine-Containing Peptides. Protein & Peptide Letters (2013) 20, 1122-1128.
84. Fujimoto Takuya; Andoh Tooru; Sudo Tamotsu; Fujita Ikuo; Moritake Hiroshi; Sugimoto Tohru; Sakuma Toshiko; Akisue Toshihiro; Kawabata Shinji; Kirihata Mitsunori; Suzuki Minoru; Sakurai Yoshinori; Ono Koji; Fukumori Yoshinobu; Kurosaka Masahiro; Ichikawa Hideki. Boron neutron capture therapy (BNCT) selectively destroys human clear cell sarcoma in mouse model. Applied radiation and isotopes: (2013), 73, 96-100.
2012
83. Hojo, Keiko; Ichikawa, Hideki; Hara, Asaki; Onishi, Mare; Kawasaki, Koichi; Fukumori, Yoshinobu. Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy: in-water synthesis of "difficult sequences", Protein & Peptide Letters (2012), 19(11), 1231-1236.
82. Songyot Anuchapreeda, Hideki Ichikawa, Siriporn Okonogi, and Yoshinobu Fukumori. Preparation of Lipid Nano-Emulsions Incorporating Curcumin. J Nanotechnol., ID 270383, 1-11 (2012).
2011
81. Hojo K, Ichikawa H, Onishi M, Fukumori Y, Kawasaki K. Peptide synthesis 'in water' by a solution-phase method using water-dispersible nanoparticle Boc-amino acid. J Pept Sci., 17(7), 487-493 (2011). Epub 2011 Apr 14.
80. Tapan K. Saha, Nikhil C. Bhoumik, Subarna Karmaker, Mahmooda G. Ahmed, Hideki Ichikawa, Yoshinobu Fukumori. Adsorption Characteristics of Reactive Black 5 from Aqueous Solution onto Chitosan, Clean–Soil, Air, Water, 984–993, 39(10), 2011.
79. T. Fujimoto, T. Andoh, T. Sudo, I. Fujita, M. Imabori, H. Moritake, T. Sugimoto, Y. Sakuma, T. Takeuchi, H. Sonobe, Alan L. Epstein, T. Akisue, M. Kirihata, M. Kurosaka, Y. Fukumori, H. Ichikawa. Evaluation of BPA uptake in clear cell sarcoma (CCS) in vitro and development of an in vivo model of CCS for BNCT studies. Appl. Rad. Isotopes, 69 (2011) 1713–1716.
78. T. Andoh, T. Fujimoto, T. Sudo, I. Fujita, M. Imabori, H. Moritake, T. Sugimoto, Y. Sakuma, T. Takeuchi, S. Kawabata, M. Kirihata, T. Akisue, K. Yayama, M. Kurosaka, S. Miyatake, Y. Fukumori, H. Ichikawa. Boron neutron capture therapy for clear cell sarcoma (CCS): Biodistribution study of p-borono-L-phenylalanine in CCS-bearing animal models. Appl. Rad. Isotopes, 69 (2011) 1721–1724.
2010
77.Tapan Kumar Saha, Nikhil Chandra Bhoumik, Subarna Karmaker, Mahmooda Ghani Ahmed, Hideki Ichikawa, Yoshinobu Fukumori. Adsorption of Methyl Orange onto Chitosan from Aqueous Solution. J. Water Resource and Protection, 2, 898-906 (2010).
76. Hui Xu, Hiroya Abe, Makio Naito, Yoshinobu Fukumori, Hideki Ichikawa, Shigehisa Endoh and Kenji Hata. Efficient dispersing and shortening of super-growth carbon nanotubes by ultrasonic treatment with ceramic balls and surfactants. Advanced Powder Technology, 21(5), 551-555 (2010).
75. Shaoning Wang, Xiaoyun Wang, Hui Xu,*, Hiroya Abe, Zhenquan Tan, Yanqiu Zhao, Jianbo Guo, Makio Naito, Hideki Ichikawa, Yoshinobu Fukumori. Towards sustained delivery of small molecular drugs using hydroxyapatite microspheres as the vehicle. Advanced Powder Technology, 21 (3), 268– 272 (2010).
2009
74. Fujimoto T, Ichikawa H, Akisue T, Fujita I, Kishimoto K, Hara H, Imabori M, Kawamitsu H, Sharma P, Brown SC, Moudgil BM, Fujii M, Yamamoto T, Kurosaka M, Fukumori Y. Accumulation of MRI contrast agents in malignant fibrous histiocytoma for gadolinium neutron capture therapy. Appl Radiat Isot. 67(7-8 Suppl):S355-8 (2009)
73. Ichikawa H, Taniguchi E, Fujimoto T, Fukumori Y: Biodistribution of BPA and BSH after single, repeated and simultaneous administrations for neutron-capture therapy of cancer. Appl Radiat Isot. 67(7-8 Suppl):S111-4 (2009).
2008
72. Hui Xua), Hiroya Abe a), Makio Naito a), Hideki Ichikawa, Yoshinobu Fukumori, Shigehisa Endoh b)： Immobilization of Highly-dispersed Single-walled Carbon Nanotubes in Biocompatible and Water-soluble Solid Matrix. J. Ceram. Soc. Japan, 116 (9), 965-968 (2008). a)大阪大学接合科学研究所．b)産業総合技術研究所．
71. Keiko Hojo, Hideki Ichikawa, Yoshinobu Fukumori, Koichi Kawasaki：Development of a Method for the Solid-Phase Peptide Synthesis in Water. Int J. Pept. Res. Ther., 14, 373-380 (2008).
70. Yaowalak Boonsongrit, Hiroya Abe, Kazuyoshi Sato, Makio Naito, Masahiro Yoshimura, Hideki Ichikawa, Yoshinobu Fukumori, Controlled release of bovine serum albumin from hydroxyapatite microspheres for protein delivery system. Materials Science and Engineering B, 148 (2008) 162–165.
69. Motoyuki Iijima, Motoyasu Yoshimura, Tadashi Tsuchiya, Mayumi Tsukada, Hideki Ichikawa, Yoshinobu Fukumori, and Hidehiro Kamiya, Direct measurement of interactions between stimulation-responsive drug delivery vehicles and artificial mucin layers by colloid probe atomic force microscopy. Langmuir, 2008, 24, 3987-3992.
2007
68. Keiko Hojo, Hideki Ichikawa, Mitsuko Maeda, Shinya Kida, Yoshinobu Fukumori, Koichi Kawasakai： Solid-phase Peptide Synthesis Using Nanoparticulate Amino Acids in Water．J. Pept. Sci., 13, 493-497 (2007)．
67. Boonsongrit Yaowalaka, Kazuyoshi Satoa, Akira Kondoa, Hiroya Abea, Makio Naitoa, Masahiro Yoshimurab, Hideki Ichikawa, Yoshinobu Fukumori：Encapsulation of protein-loaded hydroxyapatite granules with poly(lactic-co-glycolic acid)．J. Ceram. Soc. Japan, 115 (11)，745-747 (2007)．a. 大阪大学接合科学研究所，b. 東京工業大学．
66. Cathy E. McNamee, Yuki Aso, Shinpei Yamamoto, Yoshinobu Fukumori, Hideki Ichikawa, Ko Higashitani：Chemical groups that adhere to the surfaces of living malignant cells．Pharm. Res., 24(12), 2370-2380 (2007).
65. Ichikawa, H., Watanabe T., Tokumitsu H., Fukumori Y. Formulation Considerations of Gadolinium Lipid Nanoemulsion for Intravenous Delivery to Tumors in Neutron-Capture Therapy. Current Drug Delivery, 4, 131-140 (2007).
2006
64. Arimoto, M., Fukumori, Y., Fujiki, J., Ichikawa, H(. 有本昌弘 a，福森義信，藤木淳子 a，市川秀喜，2006) Acrylic terpolymer microcapsules for colon-specific drug delivery: effect of molecular weight and solubility of microencapsulated drugs on their release behaviors. J. Drug Dev. Sci. Tech., 16 (3), 173- 181.a.アルフレッサファーマ.
63. 佐々木隆史a，大原 智a，梅津光央a，名嘉 節a，阿尻雅文a，鍋田千賀，市川秀喜，福森義信(2006) 超臨界水熱法による Gd 中性子捕捉療法用新規無機ナノ粒子の調製.粉体工学会誌，43，440-444 (2006).a.東北大学多元物質科学研究所
62. Pyo,N.,Tanaka,S.,McNamee,C.E.,Kanda,Y.,Fukumori,Y.,Ichikawa,H.,Higashitani,K(.表羅英a， 田中沙綾a，キャシー・マクナミーa，神田陽一a，福森義信，市川秀喜，東谷 公a，2006)Effect of the cell type and cell density on the binding of living cells to a silica particle: An atomic force microscope study. Colloids and Surfaces B: Biointerface, 53, 278-287.a.京都大学工学研究科
61. Saha, T. K., Ichikawa, H., Fukumori, Y.(タパン・クマル・シャハ a，市川秀喜，福森義信，2006) Gadolinium diethylenetriaminopentaacetic acid-loaded chitosan microspheres for gadolinium neutron-capture therapy. Carbohydrate Res., 341, 2835-2841.a.ヤハンギノゴール大学.
60. Dongchun Liu, Hideki Ichikawa, Fude Cui, Yoshinobu Fukumori. Short-term delayed-release microcapsules spraycoated with acrylic terpolymers. Int. J. Pharm., 307, 300–307 (2006).
2005
59. Adeyeye MC, Mwangi E, Katpally S, Fujioka K, Ichikawa H, Fukumori Y.: Suspensions of prolonged-release diclofenac-Eudragit(R) and ion-exchange resin microcapsules: II. Improved dissolution stability. J. Microencapsul., 22(4), 353-362 (2005).
58. Adeyeye MC, Mwangi E, Katondo B, Jain A, Ichikawa H, Fukumori Y. Dissolution stability studies of suspensions of prolonged-release diclofenac microcapsules prepared by the Wurster process: I. Eudragit-based formulation and possible drug-excipient interaction. J. Microencapsul., 22(4), 333-342 (2005).
57. Saha TK, Karmaker S, Ichikawa H, Fukumori Y. Mechanisms and kinetics of trisodium 2-hydroxy-1,1'-azonaphthalene-3,4',6-trisulfonate adsorption onto chitosan. J. Colloid Interface Sci. 286(2), 433-439 (2005).
56. Maeda N., Hada T., Murakami-Nakai C., Kuriyama I., Ichikawa H., Fukumori. Y., Hiratsuka J., Yoshida H., Sakaguchi K., Mizushina Y.: Effects of DNA polymerase inhibitory and antitumor activities of lipase-hydrolyzed glycolipid fractions from spinach. J. Nutri. Biochem., 16, 121-128 (2005).
2004
55. Masahiro Arimoto, Hideki Ichikawa, Yoshinobu Fukumori: Microencapsulation of water-soluble macromolecules with acrylic terpolymers by the Wurster process for colon-specific drug delivery. Powder Technol., 141, 177-186 (2004).
2003
54. Hideki Ichikawa, Masahiro Arimoto, Yoshinobu Fukumori: Design of microcapsules with hydrogel as a membrane component and their preparation by a spouted bed. Powder Technol., 130, 189-192 (2003).
53. Leobandung，W., Ichikawa, H., Fukumori, Y., Peppas, N. A.(ウィリアム・レオバンダン a，市川秀喜， 福森義信，ニコラス・A.・ペパス a, 2003)Monodisperse nanoparticles of poly(ethylene glycol) macromers and N-isopropyl acrylamide for biomedical applications. J. Appl. Polym. Sci., 87, 1678-1684.a.パデュ ー大学工学部.
52. Mizushina Y., Maeda N., Kawasaki M., Ichikawa H., Murakami C., Takemura M., Xianai Xu, Sugawara F., Fukumori Y., Yoshida H., Sakaguchi K. Inhibitory Action of Emulsified Sulfoquinovosyl Acylglycerol on Mammalian DNA Polymerases. Lipids, 38 (10), 1065-1074 (2003).
2002
51. Tetsuya Watanabe, Hideki ichikawa Yoshinobu Fukumori. Tumor Accumulation of Gadolinium in Lipid-Nanoparticles intravenously Injected for Neutron-Capture Therapy of Cancer. Eur. J. Pharm. Biopharm, 54, 119-124 (2002).
50. William Leobandung, Hideki Ichikawa, Yoshinobu Fukumori, Nicholas A. Peppas. Preparation of Stable Insulin-Loaded Nanoparticles of Poly(Ethylene Glycol) Macromers and N-Isopropyl Acrylamide. J. Controlled Release, 80, 357-363 (2002)./li>
49. Futoshi Shikata, Hiroyuki Tokumitsu, Hideki Ichikawa, Yoshinobu Fukumori. In Vitro Cellular Accumulation of Gadolinium Incorporeted into Chitosan Nanoparticles Designed for Neutron-Capture Therapy of Cancer. Eur. J. Pharm. Biopharm., 53, 57-63 (2002).
2001
48. Akaho, E., Fukumori, Y., Studies on Adsorption Characteristics and Mechanism of Adsorption of Chlorhexidine Mainly by Carbon Black. J. Pharm. Sci., 90 (9), 1288-1297 (2001).
47. Ichikawa, H., Fujioka, K., Adeyeye, M. C., Fukumori, Y. Use of Ion-Exchange Resins to Prepare 100 μm-Sized Microcapsules with Prolonged Drug-Release by the Wurster Process. Int. J. Pharm., 216 (1), 67-76 (2001).
2000
46. Hideki Ichikawa, Yoshinobu Fukumori. A Novel Positively Thermosensitive Controlled-Release Microcapsule with Membrane of Nano-Sized Poly(N-isopropylacrylamide) Gel Dispersed in Ethylcellulose Matrix. J. Controlled Release, 63 (1-2), 107-119 (2000).
45. Hiroyuki Tokumitsu, Junichi Hiratsuka, Yoshinori Sakurai, Tooru Kobayashi, Hideki Ichikawa and Yoshinobu Fukumori. Gadolinium Neutron-Capture Therapy Using Novel Gadopentetic Acid-Chitosan Complex Nanoparticles: In Vivo Growth Suppression of Experimental Melanoma Solid Tumor. Cancer Letters, 150 (2), 177-182 (2000).
1999
44. Hiroyuki Tokumitsu, Hideki Ichikawa and Yoshinobu Fukumori. Chitosan-Gadopentetic Acid Complex Nanoparticles for Gadolinium Neutron-Therapy of Cancer: Preparation by Emulsion-Droplet Coalescence Technique and Characterization. Pharm. Res., 16 (12), 1830-1835 (1999).
43. Masahito Miyamoto, Kaoru Hirano, Hideki Ichikawa, Yoshinobu Fukumori, Yasuyuki Akine and Koichi Tokuuye. Biodistribution of Gadolinium Incorporated in Lipid Emulsions for Neutron-Capture Therapy with Tumor-Bearing Hamster. Biol. Pharm. Bull., 22 (12), 1331-1340 (1999).
42. Hideki Ichikawa, Yoshinobu Fukumori. Microagglomeration of Pulverized Pharmaceutical Powders Using the Wurster Process I. Preparation of Highly Drug-incorporated, Subsieve-sized Core Particles for Subsequent Microencapsulation by Film-coating. Int. J. Pharm., 180, 195-210 (1999).
41. Hideki Ichikawa, Yoshinobu Fukumori. Negatively Thermosensitive Release of Drug from Microcapsules with Hydroxypropyl Cellulose Membranes Prepared by the Wurster Process. Chem. Pharm. Bull., 47 (8),1102-1107 (1999).
40. Hiroyuki Tokumitsu, Hideki Ichikawa, Yoshinobu Fukumori, Lawrence H. Block. Preparation of Gadopentetic Acid-Loaded Chitosan Microparticles for Gadolinium Neutron-Capture Therapy of Cancer by a Novel Emulsion-Droplet Coalescence Technique. Chem. Pharm. Bull., 47 (6), 838-842 (1999).
39. Masao Hamuro,Kenji Nakamur,Yukimasa Sakai,Manabu Nakata,Hideki Ichikawa,Yoshinobu Fukumori, Ryusaku Yamada. Development of a New Oily Agent in Targeting Chemoembolization for Hepatocellular Carcinoma. Cardiovascular and Interventional Radiology, 22, 130-134 (1999).
38. Masahito Miyamoto, Kaoru Hirano, Hideki Ichikawa, Yoshinobu Fukumori, Yasuyuki Akine, Koichi Tokuuye. Preparation of Gadolinium-Containing Emulsions Stabilized with Phosphatidylcholine-Surfactant Mixtures for Neutron-Capture Therapy. Chem. Pharm. Bull., 47 (2), 203-208 (1999).
37. Kaori Jono, Hideki Ichikawa, Kazuhiro Fujioka, Yoshinobu Fukumori, Yasuyuki Akine, Koichi Tokuuye. Preparation of Lecithin Microcapsules by a Dilution Method Using the Wurster Process for Intraarterial Administration in Gadolinium Neutron-Capture Therapy.Chem. Pharm. Bull., 47 (1), 54-63 (1999).
1998
36. Tapan Kumar Saha, Kaori Jono, Hideki Ichikawa, Yoshinobu Fukumori. Preparation and Evaluation of Glutaraldehyde Cross-Linked Chitosan Microspheres as a Gadolinium Reservoir for Neutron-Capture Therapy. Chem. Pharm. Bull., 46 (3), 537-539 (1998).
35. 大迫義文，黒田隆司，藤本哲磨，市川秀喜，情野 香，福森義信.三筒付噴流層の粒子挙動に影響する要因.粉体工学会誌，35 (6), 434-438 (1998).
34. Yoshinobu Fukumori, Hiroshi Tamura, Kaori Jono, Masahito Miyamoto, Hiroyuki Tokumitsu, Hideki Ichikawa, Lawrence H. Block. Dry Grinding of Chitosan Powder by a Planetary Ball Mill. Adv. Powder Technol., 9 (4), 281-292 (1998).
33. Kaori Jono, Hideki Ichikawa, Yoshinobu Fukumori, Yoshinori Uwamino. Dissolution Properties of Gadolinium-Containing Lecithin Microcapsules Prepared by a Spouted Bed Process Assisted with a Draft Tube. Adv. Powder Technol., 9 (4), 363-375 (1998).
32. Yoshinobu Fukumori, Hideki Ichikawa, Mamoru Ueda. Preparation of Controlled Release Microcapsules by a High-Speed Elliptical-Rotor Type Mixer. Proceedings of the World Congress on Particle Technology 3, No. 120, Brighton, UK, July 7-9, 1998, Institution of Chemical Engineers, Rugby CV21 3HQ, UK.
31. HidekiIchikawa,AkihikoOhdoi,KazuhiroFujioka,YoshinobuFukumori. PreparationofMicrocapsules with Thermosensitive Hydrogel Membranes for Controlled Release Pharmaceuticals by a Spouted Bed Process. Proceedings of the World Congress on Particle Technology 3, No. 121, Brighton, UK, July 7-9,1998, Institution of Chemical Engineers, Rugby CV21 3HQ, UK.
1997
30. Kaori Jono, Hideki Ichikawa, Yoshinobu Fukumori, Ryuichi Kanamori, Yasuji Tsutsumi, Katsuko Murata,Atsuko Morimoto, Kenji Nakamura. Effect of Additives on Dissolution and Swelling of Soybean Lecithin Microcapsules Prepared Using the Wurster Process, Chem. Pharm. Bull., 45 (12), 2061-2075 (1997).
29. Masahito Miyamoto, Hideki Ichikawa, Yoshinobu Fukumori, Yasuyuki Akine, Koichi Tokuuye. Design and Preparation of Gadolinium-Reservoir Microcapsules for Neutron-Capture Therapy by Means of the Wurster Process, Chem. Pharm. Bull., 45 (12), 2043-2050 (1997).
28. Hiroyuki Tokumitsu, Yoshinobu Fukumori, Yuko Tsuda, Yoshio Okada, Fumiyo Kasuya, Kazuo Igarashi and Miyoshi Fukui. Degradation of a Novel Tripeptide, tert-Butoxycarbonyl- Try-Leu-Val-CH2Cl, with Inhibitory Effect on Human Leukocyte Elastase in Aqueous Solution and in Biological Fluids. Chem. Pharm. Bull, 45 (11), 1845-1850 (1997).
27. Hideki Ichikawa, Yoshinobu Fukumori, Christianah Moji Adeyeye. Design of Prolonged-Release Microcapsules Containing Diclofenac Sodium for Oral Suspensions and Their Preparation by the Wurster Process, Int. J. Pharm., 156, 39-48 (1997).
1996
26. Hideki Ichikawa, Shuji Kaneko, Yoshinobu Fukumori. Coating Performance of Aqueous Composite Latices with N-Isopropylacrylamide Shell and Thermosensitive Permeation Properties of Their Microcapsule Membranes. Chem. Pharm. Bull., 44(2), 383-391 (1996).
25.Kaori Jono, Hideki Ichikawa, Yoshinobu Fukumori, Ryuichi Kanamori, Yasuji Tsutsumi, Katsuko Murata, Atsuko Morimoto, Kenji Nakamura. Phase Separation in Microcapsule Membranes Composed of Soybean Lecithin, Cholesterol, Stearic Acid and Polyvinylpyrrolidone, Chem. Pharm. Bull., 44, 392-398 (1996).
1994
24. Hideki Ichikawa, Hiroyuki Tokumitsu, Kaori Jono, Tomoaki Fukuda, Yoshifumi Osako, Yoshinobu Fukumori. Coating of Pharmaceutical Powders by Fluidized Bed Process. VI. Microencapsulation Using Blend and Composite Latices of Copoly(EA-MMA-HEMA). Chem. Pharm. Bull., 42, 1308-1314 (1994).
23. Yoshinobu Fukumori, Hideki Ichikawa, Kaori Jono, Hiroyuki Tokumitsu, Toshifumi Shimizu, Ryuichi Kanamori, Yasuji Tsutsumi, Kenji Nakamura, Katsuko Murata, Atsuko Morimoto, Mitsuo Tsubakimoto, Haruki Nakatsuka, Kazuo Minakuchi, Yasuto Onoyama. Dissolution Properties of Soybean LecithinMicrocapsules for Short-Term Controlled Release Prepared Using the Wurster Process, Chem. Pharm. Bull.,42, 2604-2611 (1994).
1993
22. Yoshinobu Fukumori, Hideki Ichikawa, Kaori Jono, Tomoaki Fukuda, Yoshifumi Osako. Effect of Additives on Agglomeration in Aqueous Coating with Hydroxypropyl Cellulose, Chem. Pharm. Bull., 41, 725-730 (1993).
21. Hideki Ichikawa, Kaori Jono, Hiroyuki Tokumitsu, Tomoaki Fukuda, Yoshinobu Fukumori. Coating of Pharmaceutical Powders by Fluidized Bed Process. V. Agglomeration and Efficiency in the Coating with Aqueous Latices of Copoly(EA-MMA-HEMA), Chem. Pharm. Bull., 41, 1132-1136 (1993).
20.Yoshinobu Fukumori, Hideki Ichikawa, Hiroyuki Tokumitsu, Masahito Miyamoto, Kaori Jono, Ryuichi Kanamori, Yasuyuki Akine, Nobuhiko Tokita. Design and Preparation of Ethyl Cellulose Microcapsules of Gadopentetate Dimeglumin for Neutron Capture Therapy Using the Wurster Process, Chem. Pharm. Bull., 41, 1144-1148 (1993).
1992
19. Fumiyo Kasuya, Kazuo Igarashi, Miyoshi Fukui, Yoshinobu Fukumori, Hiroyuki Tokumitsu, Tomoaki Fukuda, Yuko Tsuda and Yoshio Okada. Liquid Chromatographic/atmospheric Pressure Chemical Ionization Mass Spectrometric Analysis of Synthetic Elastase Inhibitor Peptide. Biol. Mass Spectrometry, 21, 500-504 (1992).
18. Yasuyuki Akine, Nobuhiko Tokita, Koichi Tokuuye, Michinao Satoh, Yoshinobu Fukumori, Hiroyuki Tokumitsu, Ryuichi Kanamori, Tooru Kobayashi, Keiji Kanda. Neutron-Capture Therapy of Murine Ascites Tumor with Gadolinium-Containing Microcapsules. J. Cancer Res. Clin. Oncol., 119, 71-73 (1992).
17. YoshikazuTakeuchi,HidehitoYasukawa,YumikoYamaoka,YasukoMorimoto,SatoshiNakao,Yoshinobu Fukumori, Tomoaki Fukuda. Destabilization of Whole Skin Lipid Bio-Liposomes Induced by Skin Penetration Enhancers and FT- IR/ATR Analysis of Stratum Corneum Lipids. Chem. Pharm. Bull., 40 (2), 484-487 (1992).
16.Yoshikazu Takeuchi, Hidehito Yasukawa, Yumiko Yamaoka, Yuichi Kato, Ysuko Morimoto, Yoshinobu Fukumori, Tomoaki Fukuda. Effects of Fatty Acids, Fatty Amines and Propylene Glycol on Rate Stratum Corneum Lipids and Proteins in Vitro Measured by FT-IR/ATR Spectroscopy. Chem. Pharm. Bull., 40 (7), 1887-1892 (1992).
15.Yoshinobu Fukumori, Hideki Ichikawa, Kaori Jono, Yoshikazu Takeuchi, Tomoaki Fukuda. Computer Simulation of Agglomeration in the Wurster Process, Chem. Pharm. Bull., 40, 2159-2163 (1992).
14. Yasuyuki Akine, Nobuhiko Tokita, Koichi Tokuuye, Michinao Satoh, Yoshinobu Fukumori, Hiroyuki Tokumitsu, Ryuichi Kanamori, Tooru Kobayashi, Keiji Kanda. Neutron-Capture Therapy of Murine Ascites Tumor with Gadolinium-Containing Microcapsules. J. Cancer Res. Clin. Oncol., 119, 71-73 (1992).
13. 森本泰子、内田寛香、福森義信、福田友昭、竹内由和. クロルプロマジン誘発性膜不安定化に対 するタウリンの抑制効果. .薬剤学, 52, 166-171 (1992).
12. 森本泰子、福森義信、福田友昭、竹内由和. クロルプロマジン誘発性膜不安定化に対するタウリ ンの抑制効果のESRを用いた検討. 薬剤学, 52, 231-238 (1992).
1991
11. 村田佳津子，中村健治，椿本光男，中塚春樹，水口和夫，小野山靖人，金森隆一，福森義信.抗癌剤封入消失型マイクロカプセルの開発.日本医学放射線学会雑誌，51, 94-96 (1991).
10. Yoshinobu Fukumori, Hideki Ichikawa, Yumiko Yamaoka, Eiichi Akaho, Yoshikazu Takeuchi, Tomoaki Fukuda, Ryuichi Kanamori, Yoshifumi Osako. Microgranulation and Encapsulation of Pulverized Pharmaceutical Powders with Ethyl Cellulose by the Wurster Process. Chem. Pharm. Bull., 39 (7),1806-1812 (1991).
9. Yoshinobu Fukumori, Hideki Ichikawa, Yumiko Yamaoka, Riichi Akaho, Yoshikazu Takeuchi, Tomoaki Fukuda, Ryuichi Kanamori, Yoshifumi Osako. Effect of Additives on Physical Properties of Fine Ethyl CelluloseMicrocapsulesPreparedbytheWursterProcess. Chem.Pharm.Bull.,39(1),164-169(1991).
1990
8. IkueKaneko,YoshinobuFukumori,TomoakiFukuda,YoshikazuTakeuchi.RelationofDispositionkinetics to Pharmacological Effect of Intraveneous Administration of Chlorzoxazone in Rats. J. Pharmacobio-Dyn., 13, 367-373 (1990).
1989
7. Yoshikazu Takeuchi, Yumiko Yamaoka, Yasuko Morimoto, Ikue Kaneko, Yoshinobu Fukumori, Tomoaki Fukuda. Stabilizing Effects of Some Amino Acids on Membranes of Rabbit Erythrocytes Perturbed by Chlorpromazine. J. Pharm. Sci., 78 (1), 3-7 (1989).
6. Ikue Kaneko, Yoshinobu Fukumori, Tomoaki Fukuda, Yoshikazu Takeuchi. Influence of Alpha-Chloralose on Muscle Relaxant Effect of Chlorzoxazone in Rats and Pharmcodynamic Analysis. J. Pharmacobio- Dyn., 12, 441-447 (1989).
5. Yasuko Morimoto, Kazuyuki Kotani, Mitsuhiro Watanabe, Yoshinobu Fukumori, Tomoaki Fukuda, Yoshikazu Takeuchi. Effects of Neutral Amino Acids on Membrane Affinity of Chlorpromazine. YAKUZAIGAKU, 49 (3), 215-220 (1989).
1988
4. Ikue Kaneko, Yoshinobu Fukumori, Tomoaki Fukuda, Yoshikazu Takeuchi. Pharmacodynamics of Chlorzoxazone in Rats. J. Pharm. Sci., 77 (5), 383-386 (1988).
3. Yoshinobu Fukumori, Yumiko Yamaoka, Hideki Ichikawa, Yoshikazu Takeuchi, Tomoaki Fukuda, Yoshifumi Osako. Coating of Pharmaceutical Powders by Fluidized Bed Process. IV. Softening Temperature of Acrylic Copolymers and Its Relation to Film-Formation in Aqueous Coating. Chem. Pharm. Bull., 36 (12), 4927-4932 (1988).
2. Yoshinobu Fukumori, Yumiko Yamaoka, Hideki Ichikawa, Yoshikazu Takeuchi, Tomoaki Fukuda, Yoshifumi Osako. Coating of Pharmaceutical Powders by Fluidized Bed Process. III. Aqueous Coating with Ethyl Acrylate-Methyl Methacrylate-2-Hydroxyethyl Methacrylate Copolymer and the Dissolution Properties of the Products. Chem. Pharm. Bull., 36 (8), 3070-3078 (1988).
1. Yoshinobu Fukumori, Yumiko Yamaoka, Hideki Ichikawa, Tomoaki Fukuda, Yoshikazu Takeuchi, Yoshifumi Osako. Coating of Pharmaceutical Powders by Fluidized Bed Process. II. Microcapsules Produced by Layering of Fine Powder on Coarse Particles and Subsequent Aqueous Enteric Coating. Chem. Pharm. Bull., 36 (4), 1491-1501 (1988).